Uvaol is a natural triterpenoid compound found in various plants, particularly in olive leaves and other parts of the olive tree. It has gained attention for its potential biological activities. One of its key applications lies in anti-inflammatory therapy, where it modulates signaling pathways such as NF-κB and reduces the production of pro-inflammatory cytokines. This makes it a candidate for research in chronic inflammatory conditions like arthritis and metabolic disorders. Uvaol also shows promise in anticancer studies. It has demonstrated the ability to induce apoptosis and inhibit proliferation in certain cancer cell lines, including those of the breast, colon, and liver. Its mechanism involves cell cycle arrest and activation of mitochondrial pathways leading to programmed cell death. Additionally, uvaol exhibits antioxidant properties, helping to neutralize free radicals and reduce oxidative stress, which is beneficial in aging and neurodegenerative diseases. It has also been investigated for its antidiabetic effects, where it may improve insulin sensitivity and glucose uptake in tissues. Due to its low toxicity and natural origin, uvaol is being explored as a functional ingredient in nutraceuticals and cosmeceuticals, particularly in formulations aimed at skin protection and anti-aging.