Pre-Tocopherol (Delta-tocopherol glucoside)

  • Product Code: 126142

Tocopherol glucoside is widely used in most Avene's product as core active ingredient

(delta type - the most effective form for skin)

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Test Name Specification
Appearance Light yellow to white solid
δ-Tocopherol glucoside purity Min 98.0%
β-Tocopherol glucoside purity Max 1.0%
pH (1% aqueous solution) 5.0-7.0
Total tocopherol residue Max 0.1%
Hydration Max 2.0%
Heavy metals Max 10 ppm
Lead Max 10 ppm
Mercury Max 1 ppm
Arsenic Max 2 ppm
Cadmium Max 5 ppm
Total plate count Max 100 cfu/g
Yeast and mold Max 10 cfu/g
Thermostable coliform Negative
Staphylococcus aureus Negative
Pseudomonas aeruginosa Negative

Pre-Tocopherol (Delta-tocopherol glucoside) is a derivative of delta-tocopherol, a form of vitamin E. It is conjugated with glucose to form a glucoside, which can enhance its stability and water solubility compared to free tocopherol.

Tocopherol glucoside is widely used in most Avene's product as core active ingredient.


Below are some key points about delta-tocopherol glucoside:

Characteristics:

  1. Molecular Structure: A glucose molecule is attached to delta-tocopherol, making it a glucoside derivative.
  2. Increased Stability: The glucoside form protects the tocopherol from oxidation, extending its shelf life and making it suitable for formulations.
  3. Water Solubility: The glucoside modification improves water solubility, enabling better incorporation into aqueous systems like emulsions or hydrogels.

Applications:

  1. Cosmetics:
    • Antioxidant Properties: Provides protection against oxidative stress, helping to stabilize formulations and protect skin cells from free radical damage.
    • Skin Brightening: May contribute to a brightening effect due to its ability to interact with cellular mechanisms.
    • Anti-Aging: Works as a scavenger of free radicals, reducing signs of aging such as wrinkles and fine lines.
  2. Nutraceuticals: Potential for use in dietary supplements for enhanced bioavailability and antioxidant benefits.
  3. Pharmaceuticals: May have applications in formulations requiring stable, water-soluble forms of vitamin E derivatives.

Enzymatic Conversion in Skin:

When applied topically, delta-tocopherol glucoside can be enzymatically hydrolyzed by skin enzymes (e.g., glucosidases), releasing active delta-tocopherol. This makes it a pro-antioxidant that activates upon contact with the skin.

Benefits Over Regular Tocopherols:

  • Less prone to oxidation during storage.
  • Easier to formulate in hydrophilic systems.
  • Potentially more stable in UV-exposed products due to the glycosidic bond.

 

Use: Can be used in all kinds of Anti-aging products.

Mixing method: Mix in the water-phase, if you need to use above 0.01%, suggest to add small amount of ethanol (1-2%) in the formulation to help fully dissolve

Usage rate: 0.05-0.1%

Product characteristics: Light colored powder

Solubility: can dissolve in water (at about 0.05%), can freely dissolve in ethanol

Storage: For long term storage Store in the refrigerator at temperature 5. °C avoid light At least 3 years old

 

INCI Name : Tocopherol glucoside

Example products:

  • Glytone Age-Defying Antioxidant Day Cream
  • Avene eau thermale avène lip balm spf 30
  • Glytone Age-Defying Vitamin C + E Serum
  • Avene Sunsimed
  • Avene A-Oxitive Antioxidant Defense Serum
  • Avene A-Oxitive Antioxidant Water-Cream
  • Avene A-oxitive Day Smoothing Water-cream
  • Avene Retrinal Advanced Correcting Serum
  • Avene A-oxitive Sheetmask
  • Avene Moisturizing Self-Tanning Lotion
  • Avene Hydrance Brume
  • Avene A-Oxitive Eyes
  • Avene Milky Gel Ex
  • Avene Refreshing Eye Contour Care
  • Avene Retrinal 0.05 Cream
  • Avene Solar Body Oil SPF 30 High Protection
  • Avene Soothing Eye Contour Cream
  • Avene Sun Mist SPF30
  • Avene Ystheal Anti-Wrinkle Cream
  • Avene YsthéAL Crema
  • Avene Ysthéal Eye And Lip Contour Care
  • Avene After Sun Lait Reparateur
  • Avene Tinted Compact Cream SPF 50
  • Avene A-oxitive Night Peeling Cream
  • Avene Fluid Matifiant Hydratant
  • Avene Moisturizing Self-tanner
  • Avene Cold Cream Lip Butter
  • Avene Hyaluron Activ B3 Cell Renewal Aqua Cream-in-Gel
  • Avene Hydraterende Zelfbruiner
  • Avene Sun Cream SPF 50+ fragrance-free
  • Avene Ysthéal Anti-Wrinkle Emulsion
  • Avene Cleanance Mattifying Aqua-gel
  • Avene D-Pigment Light
  • Avene D-Pigment Riche Dark Spot Lightener
  • Avene High Protection Hydrating Lip Balm Spf50+
  • Avene Sun Fluid SPF 50+ fragrance-free
  • Avene Vitamin Aktiv Cg
  • Aveeno Soothing Radiance Mask
  • Avene Avène Hyaluron Activ B3 Eye Cream
  • Avene High Protection Tinted Compact
  • Avene Hyaluron Activ B3 Crème Fermeté Régénérante
  • Avene Hyaluron Activ B3 Renewal Firming Cream
  • Avene Sun Fluid SPF 50+ Fragranced
  • Avene Men Anti-Ageing Moisturizing Care
  • Avene Retinal 0.1 Intensive Cream


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Pre-Tocopherol (Delta-tocopherol glucoside)

Tocopherol glucoside is widely used in most Avene's product as core active ingredient

(delta type - the most effective form for skin)

Pre-Tocopherol (Delta-tocopherol glucoside) is a derivative of delta-tocopherol, a form of vitamin E. It is conjugated with glucose to form a glucoside, which can enhance its stability and water solubility compared to free tocopherol.

Tocopherol glucoside is widely used in most Avene's product as core active ingredient.


Below are some key points about delta-tocopherol glucoside:

Characteristics:

  1. Molecular Structure: A glucose molecule is attached to delta-tocopherol, making it a glucoside derivative.
  2. Increased Stability: The glucoside form protects the tocopherol from oxidation, extending its shelf life and making it suitable for formulations.
  3. Water Solubility: The glucoside modification improves water solubility, enabling better incorporation into aqueous systems like emulsions or hydrogels.

Applications:

  1. Cosmetics:
    • Antioxidant Properties: Provides protection against oxidative stress, helping to stabilize formulations and protect skin cells from free radical damage.
    • Skin Brightening: May contribute to a brightening effect due to its ability to interact with cellular mechanisms.
    • Anti-Aging: Works as a scavenger of free radicals, reducing signs of aging such as wrinkles and fine lines.
  2. Nutraceuticals: Potential for use in dietary supplements for enhanced bioavailability and antioxidant benefits.
  3. Pharmaceuticals: May have applications in formulations requiring stable, water-soluble forms of vitamin E derivatives.

Enzymatic Conversion in Skin:

When applied topically, delta-tocopherol glucoside can be enzymatically hydrolyzed by skin enzymes (e.g., glucosidases), releasing active delta-tocopherol. This makes it a pro-antioxidant that activates upon contact with the skin.

Benefits Over Regular Tocopherols:

  • Less prone to oxidation during storage.
  • Easier to formulate in hydrophilic systems.
  • Potentially more stable in UV-exposed products due to the glycosidic bond.

 

Use: Can be used in all kinds of Anti-aging products.

Mixing method: Mix in the water-phase, if you need to use above 0.01%, suggest to add small amount of ethanol (1-2%) in the formulation to help fully dissolve

Usage rate: 0.05-0.1%

Product characteristics: Light colored powder

Solubility: can dissolve in water (at about 0.05%), can freely dissolve in ethanol

Storage: For long term storage Store in the refrigerator at temperature 5. °C avoid light At least 3 years old

 

INCI Name : Tocopherol glucoside

Example products:

  • Glytone Age-Defying Antioxidant Day Cream
  • Avene eau thermale avène lip balm spf 30
  • Glytone Age-Defying Vitamin C + E Serum
  • Avene Sunsimed
  • Avene A-Oxitive Antioxidant Defense Serum
  • Avene A-Oxitive Antioxidant Water-Cream
  • Avene A-oxitive Day Smoothing Water-cream
  • Avene Retrinal Advanced Correcting Serum
  • Avene A-oxitive Sheetmask
  • Avene Moisturizing Self-Tanning Lotion
  • Avene Hydrance Brume
  • Avene A-Oxitive Eyes
  • Avene Milky Gel Ex
  • Avene Refreshing Eye Contour Care
  • Avene Retrinal 0.05 Cream
  • Avene Solar Body Oil SPF 30 High Protection
  • Avene Soothing Eye Contour Cream
  • Avene Sun Mist SPF30
  • Avene Ystheal Anti-Wrinkle Cream
  • Avene YsthéAL Crema
  • Avene Ysthéal Eye And Lip Contour Care
  • Avene After Sun Lait Reparateur
  • Avene Tinted Compact Cream SPF 50
  • Avene A-oxitive Night Peeling Cream
  • Avene Fluid Matifiant Hydratant
  • Avene Moisturizing Self-tanner
  • Avene Cold Cream Lip Butter
  • Avene Hyaluron Activ B3 Cell Renewal Aqua Cream-in-Gel
  • Avene Hydraterende Zelfbruiner
  • Avene Sun Cream SPF 50+ fragrance-free
  • Avene Ysthéal Anti-Wrinkle Emulsion
  • Avene Cleanance Mattifying Aqua-gel
  • Avene D-Pigment Light
  • Avene D-Pigment Riche Dark Spot Lightener
  • Avene High Protection Hydrating Lip Balm Spf50+
  • Avene Sun Fluid SPF 50+ fragrance-free
  • Avene Vitamin Aktiv Cg
  • Aveeno Soothing Radiance Mask
  • Avene Avène Hyaluron Activ B3 Eye Cream
  • Avene High Protection Tinted Compact
  • Avene Hyaluron Activ B3 Crème Fermeté Régénérante
  • Avene Hyaluron Activ B3 Renewal Firming Cream
  • Avene Sun Fluid SPF 50+ Fragranced
  • Avene Men Anti-Ageing Moisturizing Care
  • Avene Retinal 0.1 Intensive Cream
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