Micromul™ CD38 (Dihydroquercetin Microemulsion)
- Product Code: 125156
dihydroquercetin liquid preparation
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| Test Name | Specification |
|---|---|
| Appearance | Yellow liquid |
| Odor | Slight characteristics |
| Dihydroquercetin content (% w/w) | 2.5-3.5 |
| Heavy Metals (Total) | 10ppm Max |
| Heavy Metals (Arsenic) | 1ppm Max |
| Microbes - Total viable aerobic count | 100cfu/g Max |
| Microbes - Fungi, yeasts and moulds | 50cfu/g Max |
| Microbes - Pathogens | Absent |
Micromul™ CD38 (Dihydroquercetin Microemulsion)
Dihydroquercetin (taxifolin) has been identified as a natural inhibitor of CD38, an enzyme that plays a key role in cellular metabolism, specifically in the regulation of nicotinamide adenine dinucleotide (NAD+). CD38 activity contributes to the degradation of NAD+, a molecule essential for many biological processes, including energy metabolism, DNA repair, and the activation of sirtuins, which are proteins involved in aging regulation and stress resistance.
Summary of skin benefits of Micromul™ CD38
| Benefit | Description | Scientific Basis |
|---|---|---|
| Antioxidant Protection | Dihydroquercetin is a powerful antioxidant that neutralizes free radicals, reducing oxidative stress that causes premature aging, wrinkles, and skin damage. | Proven to scavenge reactive oxygen species (ROS), protecting skin cells from damage caused by UV radiation (Topal et al., 2016; Micek et al., 2021). |
| CD38 Inhibition & NAD+ Boost | Inhibits CD38 enzyme activity, preserving NAD+ levels essential for DNA repair, mitochondrial function, and activating anti-aging sirtuins (SIRT1). | Higher NAD+ levels are linked to better energy metabolism, enhanced DNA repair, and slower aging (Lee et al., 2021; Micek et al., 2021). |
| Anti-Inflammatory Effects | Reduces inflammation in the skin, addressing chronic low-grade inflammation (inflammaging) that accelerates skin aging. | Inhibition of CD38 is associated with reduced inflammation, leading to less collagen breakdown and slower wrinkle formation (Chen & Zhang, 2018; Micek et al., 2021). |
| Improves Skin Elasticity | Enhances skin viscoelasticity, improving firmness and reducing sagging. | A study showed significant improvement in skin elasticity after using a 3% dihydroquercetin cream (Micek et al., 2021). |
| Reduces Hyperpigmentation | Decreases melanin production and helps brighten skin tone, addressing age spots and uneven pigmentation. | Proven reduction in melanin content and skin brightening after application of dihydroquercetin (An et al., 2008; Micek et al., 2021). |
| DNA Repair & Photoprotection | Enhances DNA repair mechanisms and reduces UV-induced skin damage, supporting skin health and reducing signs of photoaging. | Dihydroquercetin’s antioxidant properties help prevent UV-induced DNA damage and promote effective repair (Oi et al., 2012; Micek et al., 2021). |
| Supports Mitochondrial Function | Maintains mitochondrial health by preserving NAD+, ensuring cells have the energy needed for skin repair and renewal, contributing to healthier, more youthful skin. | Improved mitochondrial function leads to better skin repair processes and slower aging (Wang et al., 2006; Micek et al., 2021). |
| Non-Irritant & Safe for All Skin Types | Micromul™ CD38 has been shown to be non-irritating and suitable for sensitive skin, making it ideal for broad-spectrum skincare use. | No allergic or irritant reactions observed in studies (Micek et al., 2021). |
Usage: For all kinds of cosmetics.
Mixing method: dissolve in water
Usage rate: 0.1-3%
Product characteristics: Light yellow liquid
Solubility: Can be dissolved in water
Storage: For long-term storage Store in the refrigerator. Avoid sunlight and heat. At least 2 years old
INCI Name : Polysorbate 80, Dimethyl Isosorbide, Dihydroquercetin, Propanediol, Ethylhexylglycerin
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Micromul™ CD38 (Dihydroquercetin Microemulsion)
dihydroquercetin liquid preparation
Micromul™ CD38 (Dihydroquercetin Microemulsion)
Dihydroquercetin (taxifolin) has been identified as a natural inhibitor of CD38, an enzyme that plays a key role in cellular metabolism, specifically in the regulation of nicotinamide adenine dinucleotide (NAD+). CD38 activity contributes to the degradation of NAD+, a molecule essential for many biological processes, including energy metabolism, DNA repair, and the activation of sirtuins, which are proteins involved in aging regulation and stress resistance.
Summary of skin benefits of Micromul™ CD38
| Benefit | Description | Scientific Basis |
|---|---|---|
| Antioxidant Protection | Dihydroquercetin is a powerful antioxidant that neutralizes free radicals, reducing oxidative stress that causes premature aging, wrinkles, and skin damage. | Proven to scavenge reactive oxygen species (ROS), protecting skin cells from damage caused by UV radiation (Topal et al., 2016; Micek et al., 2021). |
| CD38 Inhibition & NAD+ Boost | Inhibits CD38 enzyme activity, preserving NAD+ levels essential for DNA repair, mitochondrial function, and activating anti-aging sirtuins (SIRT1). | Higher NAD+ levels are linked to better energy metabolism, enhanced DNA repair, and slower aging (Lee et al., 2021; Micek et al., 2021). |
| Anti-Inflammatory Effects | Reduces inflammation in the skin, addressing chronic low-grade inflammation (inflammaging) that accelerates skin aging. | Inhibition of CD38 is associated with reduced inflammation, leading to less collagen breakdown and slower wrinkle formation (Chen & Zhang, 2018; Micek et al., 2021). |
| Improves Skin Elasticity | Enhances skin viscoelasticity, improving firmness and reducing sagging. | A study showed significant improvement in skin elasticity after using a 3% dihydroquercetin cream (Micek et al., 2021). |
| Reduces Hyperpigmentation | Decreases melanin production and helps brighten skin tone, addressing age spots and uneven pigmentation. | Proven reduction in melanin content and skin brightening after application of dihydroquercetin (An et al., 2008; Micek et al., 2021). |
| DNA Repair & Photoprotection | Enhances DNA repair mechanisms and reduces UV-induced skin damage, supporting skin health and reducing signs of photoaging. | Dihydroquercetin’s antioxidant properties help prevent UV-induced DNA damage and promote effective repair (Oi et al., 2012; Micek et al., 2021). |
| Supports Mitochondrial Function | Maintains mitochondrial health by preserving NAD+, ensuring cells have the energy needed for skin repair and renewal, contributing to healthier, more youthful skin. | Improved mitochondrial function leads to better skin repair processes and slower aging (Wang et al., 2006; Micek et al., 2021). |
| Non-Irritant & Safe for All Skin Types | Micromul™ CD38 has been shown to be non-irritating and suitable for sensitive skin, making it ideal for broad-spectrum skincare use. | No allergic or irritant reactions observed in studies (Micek et al., 2021). |
Usage: For all kinds of cosmetics.
Mixing method: dissolve in water
Usage rate: 0.1-3%
Product characteristics: Light yellow liquid
Solubility: Can be dissolved in water
Storage: For long-term storage Store in the refrigerator. Avoid sunlight and heat. At least 2 years old
INCI Name : Polysorbate 80, Dimethyl Isosorbide, Dihydroquercetin, Propanediol, Ethylhexylglycerin
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