Glutamylamidoethyl Imidazole (eq. Chronocyclin Solution)
- Product Code: 126178
a synthetic chronopeptide utilized in topical skincare formulations for its potential anti-aging benefits. It is designed to mimic the effects of sun exposure on circadian gene expression, thereby helping to synchronize the skin's biorhythm
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| Test Name | Specification |
|---|---|
| Appearance | Colorless to pale yellow transparent liquid |
| Odor | Characteristic odor |
| Content (%) | 0.5 - 1.5% |
| PH (2% aqueous dispersion, 25°C) | 5.00 - 8.00 |
| Aerobic plate (CFU/ml) | Max 100 CFU/ml |
| Yeast & Molds (CFU/ml) | Max 10 CFU/ml |
| Escherichia coli | Negative |
| Pseudomonas aeruginosa | Negative |
| Staphylococcus aureus | Negative |
| Heavy metal (ppm) | Max 20 ppm |
Glutamylamidoethyl Imidazole (eq. Chronocyclin Solution)
a synthetic chronopeptide utilized in topical skincare formulations for its potential anti-aging benefits. It is designed to mimic the effects of sun exposure on circadian gene expression, thereby helping to synchronize the skin's biorhythm. This synchronization is crucial, as disruptions in the skin's circadian rhythm—due to factors like stress, lack of sleep, or irregular sun exposure—can impair cellular functions, including metabolism, regeneration, and recovery.
By promoting the expression of circadian genes, glutamylamidoethyl imidazole aims to enhance the skin's natural defense mechanisms and optimize cellular functions. This process may lead to improved skin regeneration, increased production of vitamin D, and overall healthier skin.
The ingredient is particularly recommended for individuals experiencing skin fatigue due to stress, jet lag, or insufficient sun exposure. Regular application in topical products may result in a more rested and rejuvenated complexion, with potential improvements in skin elasticity, texture, and appearance.
| Skin Benefit | Mechanism/Action | Research Evidence |
|---|---|---|
| Optimized Vitamin D activity | Promotes enzymatic expression for Vitamin D bio-transformation. | In vitro tests on reconstructed epidermis. |
| Resynchronized circadian rhythms | Mimics sun exposure to activate circadian genes. | Studies showing UV-mimicking activity. |
| Stimulated circadian genes | Stimulates CLOCK and PERIOD-1 gene expression. | Gene expression monitored over time. |
| Improved natural cell defenses | Strengthens defenses against UV and pollution. | Laboratory skin defense activation tests. |
| Enhanced skin regeneration | Enhances keratinocyte and fibroblast activity. | Epidermal regeneration studies. |
| Anti-aging effects | Improves microcirculation and nutrient supply. | Microcirculation tracking experiments. |
| Reduction of skin fatigue and stress | Revitalizes skin under stress, jet lag, or lack of sun. | Tests on skin recovery from stress and fatigue. |
Usage: in any skin care products
Mixing method: Blend or stir to distribute in water. By avoiding heat above 40C.
Usage rate: 0.2-1.0%
Product characteristics: clear liquid
Solubility: Can be dissolved in water without using heat
Storage: Can be stored at room temperature But close the bottle cap tightly. Then completely protected from sunlight or heat. The product has a minimum shelf life of 2 years.
INCI Name : Water, Butylene Glycol, Glutamylamidoethyl Imidazole
Example products:
CHANEL SUBLIMAGE L'EXTRAIT DE NUIT
Drunk Elephant C-Firma Fresh Day Serum C
MURAD Night Fix Enzyme Treatment
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Glutamylamidoethyl Imidazole (eq. Chronocyclin Solution)
a synthetic chronopeptide utilized in topical skincare formulations for its potential anti-aging benefits. It is designed to mimic the effects of sun exposure on circadian gene expression, thereby helping to synchronize the skin's biorhythm
Glutamylamidoethyl Imidazole (eq. Chronocyclin Solution)
a synthetic chronopeptide utilized in topical skincare formulations for its potential anti-aging benefits. It is designed to mimic the effects of sun exposure on circadian gene expression, thereby helping to synchronize the skin's biorhythm. This synchronization is crucial, as disruptions in the skin's circadian rhythm—due to factors like stress, lack of sleep, or irregular sun exposure—can impair cellular functions, including metabolism, regeneration, and recovery.
By promoting the expression of circadian genes, glutamylamidoethyl imidazole aims to enhance the skin's natural defense mechanisms and optimize cellular functions. This process may lead to improved skin regeneration, increased production of vitamin D, and overall healthier skin.
The ingredient is particularly recommended for individuals experiencing skin fatigue due to stress, jet lag, or insufficient sun exposure. Regular application in topical products may result in a more rested and rejuvenated complexion, with potential improvements in skin elasticity, texture, and appearance.
| Skin Benefit | Mechanism/Action | Research Evidence |
|---|---|---|
| Optimized Vitamin D activity | Promotes enzymatic expression for Vitamin D bio-transformation. | In vitro tests on reconstructed epidermis. |
| Resynchronized circadian rhythms | Mimics sun exposure to activate circadian genes. | Studies showing UV-mimicking activity. |
| Stimulated circadian genes | Stimulates CLOCK and PERIOD-1 gene expression. | Gene expression monitored over time. |
| Improved natural cell defenses | Strengthens defenses against UV and pollution. | Laboratory skin defense activation tests. |
| Enhanced skin regeneration | Enhances keratinocyte and fibroblast activity. | Epidermal regeneration studies. |
| Anti-aging effects | Improves microcirculation and nutrient supply. | Microcirculation tracking experiments. |
| Reduction of skin fatigue and stress | Revitalizes skin under stress, jet lag, or lack of sun. | Tests on skin recovery from stress and fatigue. |
Usage: in any skin care products
Mixing method: Blend or stir to distribute in water. By avoiding heat above 40C.
Usage rate: 0.2-1.0%
Product characteristics: clear liquid
Solubility: Can be dissolved in water without using heat
Storage: Can be stored at room temperature But close the bottle cap tightly. Then completely protected from sunlight or heat. The product has a minimum shelf life of 2 years.
INCI Name : Water, Butylene Glycol, Glutamylamidoethyl Imidazole
Example products:
CHANEL SUBLIMAGE L'EXTRAIT DE NUIT
Drunk Elephant C-Firma Fresh Day Serum C
MURAD Night Fix Enzyme Treatment
| Mechanism | - |
| Appearance | - |
| Longevity | - |
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| Heat Resistance | - |
| Stable in pH range | - |
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