Here is a marketing-oriented scientific summary of the key points about sclareol from the research paper:
Sclareol: An Effective Botanical Ingredient for Improving Skin Aging and Wrinkles
Please see detail anti-wrinkle effect on the attached research paper.
- Sclareol is a naturally-derived compound isolated from the plant Salvia officinalis (sage). It has a history of use in the cosmetic and fragrance industries.
- Research shows sclareol has potent anti-photoaging effects, making it an excellent candidate ingredient for skincare products aimed at reducing the visible signs of skin aging.
- In human skin cells and 3D skin models, sclareol:
- Stimulated cell proliferation and protected against UV-induced cell death
- Inhibited the expression of key matrix metalloproteinase (MMP) enzymes that degrade collagen and contribute to wrinkle formation
- Reduced activation of the AP-1 transcription factor that regulates MMPs
- Helped maintain epidermal thickness and stimulated growth of new skin cells after UV exposure
- In a clinical study, a 0.02% sclareol-containing cream significantly improved the appearance of facial wrinkles around the eyes after 12 weeks of use, with no adverse effects.
The scientific data demonstrates sclareol's efficacy as an anti-aging botanical active. Its ability to protect against UV-induced skin damage and visibly reduce wrinkles makes it a valuable addition to cosmetic formulations targeting signs of skin aging. Formulators can leverage sclareol's unique properties to develop high-performing, natural-origin anti-aging skincare products.
Usage rate: 0.1-0.2%
Product appearance: white/light color powder It has a natural smell.
Solubility: Can be dissolved in oil, glycol, alcohol.
Storage: Store in a cool place. Do not expose to light and heat. At least 24 months old
INCI Name : Sclareol
