a natural citrus bioflavonoid, is extracted from the dry buds of sophora japonical. Rutin is a phenolic antioxidant and has been demonstrated to scavenge superoxide radicals. Rutin can chelate metal ions, such as iron, thereby reducing the Fenton reaction (production of damaging oxygen radicals). Rutin is classified as vitamin P which increases the strength of the walls of the blood capillaries and regulates their permeability