Pefloxacin is primarily used as an antibiotic to treat various bacterial infections. It is effective against a wide range of Gram-negative and Gram-positive bacteria, making it useful in treating infections such as urinary tract infections, respiratory tract infections, skin and soft tissue infections, and bone and joint infections. Additionally, it is often employed in the management of gastrointestinal infections caused by susceptible organisms. Pefloxacin is also used in some cases for the treatment of sexually transmitted infections like gonorrhea. Its ability to penetrate tissues and body fluids effectively makes it a suitable choice for systemic infections. However, it is important to use it under medical supervision due to potential side effects and the risk of antibiotic resistance.