Tildipirosin is primarily used in veterinary medicine as an antimicrobial agent to treat respiratory diseases in cattle and swine. It is effective against a range of bacterial pathogens, including *Mannheimia haemolytica*, *Pasteurella multocida*, and *Actinobacillus pleuropneumoniae*, which are commonly associated with bovine and porcine respiratory infections. The compound is administered via injection, providing a prolonged therapeutic effect due to its long half-life, which reduces the need for frequent dosing. Its use helps improve animal health, reduce mortality rates, and enhance productivity in livestock farming. Additionally, tildipirosin's targeted action minimizes the risk of resistance development, making it a valuable tool in veterinary healthcare.