Besifloxacin HCl is primarily used as an ophthalmic antibiotic to treat bacterial infections of the eye. It is effective against a broad spectrum of bacteria, making it suitable for treating conditions like bacterial conjunctivitis. The medication works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication and repair. Its formulation as an eye drop ensures targeted delivery, minimizing systemic absorption and reducing the risk of side effects. Besifloxacin HCl is often prescribed when other treatments are ineffective or when a broad-spectrum antibiotic is needed. It is typically applied directly to the affected eye(s) as directed by a healthcare provider, ensuring quick relief from symptoms such as redness, discharge, and irritation.