Used in the synthesis of rifamycin-based antibiotics, particularly as an intermediate in modifying the pharmacokinetic properties of rifapentine. Enhances stability and alters metabolic pathways, supporting development of long-acting tuberculosis treatments. Investigated for improved dosing regimens in latent TB infection due to slower clearance and extended half-life in formulations. Also serves as a reference standard in analytical testing to assess purity and degradation products in rifamycin derivatives.