Puromycin aminonucleoside
98%
- Product Code: 96403
Alias:
Aminonucleoside puromycin; vitamin E acetate
CAS:
58-60-6
Properties:
Puromycin aminonucleoside is an aminonucleoside antibiotic that is an analog of puromycin but does not affect protein synthesis or induce apoptosis. the
| Molecular Weight: | 294.31 g./mol | Molecular Formula: | C₁₂H₁₈N₆O₃ |
|---|---|---|---|
| EC Number: | 200-388-3 | MDL Number: | MFCD00063462 |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8°C |
Product Description:
Puromycin aminonucleoside is primarily used in biochemical research to study protein synthesis and cellular processes. It acts as an inhibitor of protein synthesis by mimicking the structure of aminoacyl-tRNA, causing premature termination of translation. This property makes it a valuable tool in experiments aimed at understanding ribosome function and the mechanisms of translation.
In cell biology, it is employed to select cells that have been genetically modified to express resistance to puromycin aminonucleoside. This allows researchers to isolate and study specific populations of cells, such as those expressing a particular gene or undergoing a specific cellular pathway.
Additionally, puromycin aminonucleoside is used in studies related to kidney diseases, particularly in the development of animal models for nephrotic syndrome. Its ability to induce proteinuria and glomerular damage in experimental models helps researchers investigate the pathophysiology of kidney disorders and test potential therapeutic interventions.
Overall, puromycin aminonucleoside serves as a critical reagent in molecular biology and biomedical research, aiding in the exploration of protein synthesis, genetic modifications, and kidney disease mechanisms.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to light yellow Solid |
| PURITY | 97.5-100 |
| CARBONC | 48.47 % 49.47 % |
| NITROGENN | 28.06 % 29.06 % |
| MELTING POINT | 215-225 |
| SOLUBILITY IN HOT WATER | Colorless to Yellow,Cle ar to Slightly Hazy,50mg/ml |
| UV Lambda max0.1N HCl | 267 nm 268 nm |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | ฿8,460.00 |
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Puromycin aminonucleoside
Puromycin aminonucleoside is primarily used in biochemical research to study protein synthesis and cellular processes. It acts as an inhibitor of protein synthesis by mimicking the structure of aminoacyl-tRNA, causing premature termination of translation. This property makes it a valuable tool in experiments aimed at understanding ribosome function and the mechanisms of translation.
In cell biology, it is employed to select cells that have been genetically modified to express resistance to puromycin aminonucleoside. This allows researchers to isolate and study specific populations of cells, such as those expressing a particular gene or undergoing a specific cellular pathway.
Additionally, puromycin aminonucleoside is used in studies related to kidney diseases, particularly in the development of animal models for nephrotic syndrome. Its ability to induce proteinuria and glomerular damage in experimental models helps researchers investigate the pathophysiology of kidney disorders and test potential therapeutic interventions.
Overall, puromycin aminonucleoside serves as a critical reagent in molecular biology and biomedical research, aiding in the exploration of protein synthesis, genetic modifications, and kidney disease mechanisms.
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