Used in research to detect and quantify ERK1/2 protein activation in cellular signaling pathways. Commonly applied in Western blotting, immunohistochemistry, and ELISA to study cell proliferation, differentiation, and apoptosis. Helps investigate the role of MAPK signaling in cancer, inflammation, and neurodegenerative diseases. Enables monitoring of phosphorylation states of ERK1/2, providing insight into drug responses and pathway modulation in experimental models.