Used primarily in the treatment of obsessive-compulsive disorder (OCD) in adults and children. It helps reduce repetitive thoughts and behaviors, improving daily functioning. Also prescribed for major depressive disorder, especially when other antidepressants are ineffective. Has activity in managing chronic pain conditions such as neuropathic pain due to its effect on nerve signaling. Sometimes used off-label for panic disorder, cataplexy in narcolepsy, and certain anxiety-related conditions. Its sedative properties may help patients with depression who also suffer from insomnia or agitation.