Vortioxetine HBr is primarily used as an antidepressant in the treatment of major depressive disorder (MDD). It works by modulating serotonin levels in the brain, which helps improve mood, energy levels, and feelings of well-being. Additionally, it is known to enhance cognitive function, particularly in patients experiencing cognitive impairment associated with depression. This makes it a valuable option for individuals who struggle with both emotional and cognitive symptoms. It is often prescribed when other antidepressants have not been effective or have caused undesirable side effects. The medication is typically taken orally and requires consistent use over several weeks to achieve optimal therapeutic effects.