(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
99%
Reagent
Code: #246554
Alias
4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-A]pyrazine-7-(8H)-yl]-1-(2,4,5-trifluorophenyl)-2-butanone
CAS Number
764667-65-4
science Other reagents with same CAS 764667-65-4
blur_circular Chemical Specifications
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Molecular Information
Weight
406.28 g/mol
Formula
C₁₆H₁₂F₆N₄O₂
thermostat
Physical Properties
Melting Point
82-84°C
Boiling Point
513.902ºC at 760 mmHg
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Storage & Handling
Storage
-20℃
description Product Description
Used as a key intermediate in the synthesis of sitagliptin, a medication for type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood sugar levels. Its structure allows for high selectivity and potency in the final pharmaceutical product. Widely utilized in active pharmaceutical ingredient (API) manufacturing due to its stability and reactivity profile in multi-step synthesis.
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