(Z)-5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione

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Reagent Code: #246742
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CAS Number 154052-92-3

science Other reagents with same CAS 154052-92-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 221.23 g/mol
Formula C₁₀H₇NO₃S
badge Registry Numbers
MDL Number MFCD00711076
thermostat Physical Properties
Melting Point >300 °C
inventory_2 Storage & Handling
Density 1.542±0.06 g/cm3(Predicted)
Storage Room temperature

description Product Description

Used in pharmaceutical research as a key scaffold for developing antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as an intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), which regulates glucose and lipid metabolism. Additionally, derivatives of this compound are explored for their antioxidant and anti-inflammatory properties, making them candidates for treating metabolic disorders and neurodegenerative diseases. Its (Z)-configuration is critical for biological activity, influencing binding affinity and potency in drug design.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,500.00
inventory 250mg
10-20 days ฿9,910.00
inventory 1g
10-20 days ฿20,410.00

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(Z)-5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione
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Used in pharmaceutical research as a key scaffold for developing antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as an intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), which regulates glucose and lipid metabolism. Additionally, derivatives of this compound are explored for their antioxidant and anti-inflammatory properties, making them candidates for treating metabolic disorders and neurodegenerative diseases. Its (Z)-configuration is critical for biological activity, influencing binding affinity and potency in drug design.
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