(Z)-5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione
95%
Reagent
Code: #246742
CAS Number
154052-92-3
science Other reagents with same CAS 154052-92-3
blur_circular Chemical Specifications
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Molecular Information
Weight
221.23 g/mol
Formula
C₁₀H₇NO₃S
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Registry Numbers
MDL Number
MFCD00711076
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Physical Properties
Melting Point
>300 °C
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Storage & Handling
Density
1.542±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key scaffold for developing antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as an intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), which regulates glucose and lipid metabolism. Additionally, derivatives of this compound are explored for their antioxidant and anti-inflammatory properties, making them candidates for treating metabolic disorders and neurodegenerative diseases. Its (Z)-configuration is critical for biological activity, influencing binding affinity and potency in drug design.
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