CLP257
≥98%(HPLC)
Reagent
Code: #121129
CAS Number
1181081-71-9
blur_circular Chemical Specifications
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Molecular Information
Weight
307.34 g/mol
Formula
C₁₄H₁₄FN₃O₂S
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Registry Numbers
MDL Number
MFCD28166488
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Storage & Handling
Density
1.50±0.1 g/cm3
Storage
2-8°C
description Product Description
CLP257 is primarily investigated for its potential therapeutic applications in the field of neuroscience. It functions as a positive allosteric modulator of the KCC2 transporter, which plays a critical role in regulating chloride ion homeostasis in neurons. By enhancing KCC2 activity, CLP257 has shown promise in restoring normal neuronal function in conditions characterized by impaired chloride transport, such as epilepsy, neuropathic pain, and certain psychiatric disorders. Preclinical studies suggest that it may help alleviate hyperexcitability in neural circuits, making it a candidate for developing treatments for these conditions. However, further research is needed to fully understand its efficacy and safety in clinical settings.
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CLP257
CLP257 is primarily investigated for its potential therapeutic applications in the field of neuroscience. It functions as a positive allosteric modulator of the KCC2 transporter, which plays a critical role in regulating chloride ion homeostasis in neurons. By enhancing KCC2 activity, CLP257 has shown promise in restoring normal neuronal function in conditions characterized by impaired chloride transport, such as epilepsy, neuropathic pain, and certain psychiatric disorders. Preclinical studies suggest that it may help alleviate hyperexcitability in neural circuits, making it a candidate for developing treatments for these conditions. However, further research is needed to fully understand its efficacy and safety in clinical settings.
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