CLP257

≥98%(HPLC)

Reagent Code: #121129
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CAS Number 1181081-71-9

blur_circular Chemical Specifications

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Weight 307.34 g/mol
Formula C₁₄H₁₄FN₃O₂S
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MDL Number MFCD28166488
inventory_2 Storage & Handling
Density 1.50±0.1 g/cm3
Storage 2-8°C

description Product Description

CLP257 is primarily investigated for its potential therapeutic applications in the field of neuroscience. It functions as a positive allosteric modulator of the KCC2 transporter, which plays a critical role in regulating chloride ion homeostasis in neurons. By enhancing KCC2 activity, CLP257 has shown promise in restoring normal neuronal function in conditions characterized by impaired chloride transport, such as epilepsy, neuropathic pain, and certain psychiatric disorders. Preclinical studies suggest that it may help alleviate hyperexcitability in neural circuits, making it a candidate for developing treatments for these conditions. However, further research is needed to fully understand its efficacy and safety in clinical settings.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿9,405.00
CLP257
CLP257 is primarily investigated for its potential therapeutic applications in the field of neuroscience. It functions as a positive allosteric modulator of the KCC2 transporter, which plays a critical role in regulating chloride ion homeostasis in neurons. By enhancing KCC2 activity, CLP257 has shown promise in restoring normal neuronal function in conditions characterized by impaired chloride transport, such as epilepsy, neuropathic pain, and certain psychiatric disorders. Preclinical studies suggest that it may help alleviate hyperexcitability in neural circuits, making it a candidate for developing treatments for these conditions. However, further research is needed to fully understand its efficacy and safety in clinical settings.
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