Coptisine sulfate is a bioactive alkaloid salt widely used in traditional Chinese medicine for its antimicrobial, anti-inflammatory, and antioxidant properties. It is commonly incorporated into herbal formulations to treat gastrointestinal disorders, such as diarrhea, dysentery, and gastritis, by inhibiting bacterial growth and reducing inflammation and abdominal pain. Research highlights its potential anti-cancer effects, including inducing apoptosis in certain cancer cells and inhibiting tumor growth. Additionally, it shows promise in managing diabetes by helping to lower blood sugar levels. In skincare products, it is utilized to reduce inflammation and treat acne. Its role in traditional medicine also involves balancing the body and alleviating 'heat' symptoms.