Dermaseptin, derived from the skin secretion of the Phyllomedusa sauvagii frog, is primarily recognized for its potent antimicrobial properties. It is extensively studied for its ability to combat a wide range of pathogens, including bacteria, fungi, and viruses. This peptide is particularly valued in medical research for developing new antimicrobial agents, especially in the context of increasing antibiotic resistance. Its mechanism involves disrupting microbial cell membranes, leading to cell death, which makes it a promising candidate for treating infections that are resistant to conventional antibiotics. Additionally, Dermaseptin is explored for its potential in wound healing applications, where its antimicrobial activity can prevent infections while promoting tissue repair. Researchers are also investigating its use in cancer therapy, as it has shown the ability to selectively target and destroy cancer cells without harming normal cells. In the cosmetic industry, Dermaseptin is being considered for its preservative qualities in skincare products, offering a natural alternative to synthetic antimicrobials. Its broad-spectrum activity and minimal resistance development make it a versatile and valuable compound in both therapeutic and industrial applications.