Monepantel is primarily used in veterinary medicine as an anthelmintic agent to treat parasitic worm infections in livestock, particularly in sheep and cattle. It is effective against a broad spectrum of gastrointestinal nematodes, including those resistant to other classes of anthelmintics. The compound works by selectively targeting parasite-specific receptors, disrupting their nervous system and leading to paralysis and death of the parasites. Its application helps improve animal health, productivity, and overall welfare by reducing the burden of parasitic infections. Monepantel is administered orally, often in the form of a drench or feed additive, making it convenient for use in farm settings. Its unique mode of action also makes it a valuable tool in managing anthelmintic resistance in livestock populations.