Clozic is primarily used in the treatment of schizophrenia, particularly for patients who have not responded adequately to other antipsychotic medications. It is effective in managing symptoms such as hallucinations, delusions, and disorganized thinking. Additionally, Clozic is often prescribed for reducing the risk of suicidal behavior in patients with schizophrenia or schizoaffective disorder. Due to its potential for serious side effects, such as agranulocytosis, its use is closely monitored, and regular blood tests are required to ensure patient safety. It is considered a second-line treatment, reserved for cases where other therapies have failed.