Used in biomedical research to detect and quantify caspase-9 levels in cell lysates or tissue samples. Plays a key role in apoptosis studies, particularly in understanding mitochondrial-mediated cell death pathways. Widely applied in cancer research to evaluate the activation of caspase-9 during chemotherapy-induced apoptosis. Also utilized in neurodegenerative disease studies where dysregulation of apoptotic signaling is involved. Supports drug development by assessing compound effects on caspase-9 activity in experimental models.