1-(2-amino-3-chlorophenyl)-2,2,2-trifluoroethanone
≥95%
Reagent
Code: #135152
CAS Number
1414958-52-3
blur_circular Chemical Specifications
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Molecular Information
Weight
223.58 g/mol
Formula
C₈H₅ClF₃NO
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Registry Numbers
MDL Number
MFCD22689228
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective kinase inhibitors. Its trifluoromethyl ketone group enables strong hydrogen bonding and dipole interactions, enhancing binding affinity in drug-receptor complexes. Commonly employed in the preparation of bioactive molecules targeting inflammatory and neurological disorders. Also utilized in agrochemical research for designing novel pesticides with improved metabolic stability. The presence of both amino and chloro substituents allows for further functionalization via cross-coupling or nucleophilic substitution reactions, making it valuable in medicinal chemistry campaigns.
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