(2,4-Difluoro-3-formylphenyl)boronic acid
95%
Reagent
Code: #176571
CAS Number
870718-06-2
blur_circular Chemical Specifications
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Molecular Information
Weight
185.92 g/mol
Formula
F₂C₆H₂(CHO)B(OH)₂
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Registry Numbers
MDL Number
MFCD04974116
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Physical Properties
Melting Point
206 - 210 ℃ - lit.
Boiling Point
332.5 ℃ at 760 mmHg
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Storage & Handling
Density
1.42±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its aldehyde and boronic acid functional groups allow for versatile coupling reactions, such as Suzuki-Miyaura cross-coupling and imine formation, enabling the construction of complex drug-like molecules. Commonly employed in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability in target molecules. Also utilized in the preparation of fluorescent probes and sensors owing to its reactivity with nucleophiles and ability to coordinate with diols in saccharide detection.
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