tert-Butyl 1,2,5-triazaspiro[2.4]hept-1-ene-5-carboxylate
95%
Reagent
Code: #142180
CAS Number
2170217-09-9
blur_circular Chemical Specifications
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Molecular Information
Weight
197.24 g/mol
Formula
C₉H₁₅N₃O₂
thermostat
Physical Properties
Boiling Point
269.9±50.0 °C(Predicted)
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Storage & Handling
Density
1.29±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a protected synthon in organic synthesis, particularly in the preparation of nitrogen-containing heterocycles and bioactive molecules. Its spirocyclic structure and masked amine functionality make it valuable in medicinal chemistry for building constrained analogs of amino acids or amines. The tert-butyl carbamate (Boc) group allows for selective deprotection under mild acidic conditions, enabling stepwise assembly of complex molecules. Commonly employed in the synthesis of kinase inhibitors, GPCR ligands, and other pharmaceutical intermediates where steric and electronic control of nitrogen reactivity is required.
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