Azido-PEG6-acid is widely used in bioconjugation and click chemistry applications. Its azide group enables efficient reactions with alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it valuable for labeling biomolecules such as proteins, peptides, and nucleic acids. The PEG6 spacer enhances solubility and reduces steric hindrance, improving reaction efficiency and stability of the conjugates. This compound is also employed in the development of drug delivery systems, where it facilitates the attachment of targeting ligands or therapeutic agents to carrier molecules. Additionally, it is utilized in surface modification and functionalization of materials for biomedical research, enabling the creation of bioactive surfaces for cell studies or biosensor applications. Its versatility makes it a key reagent in chemical biology and materials science.