This chemical is widely used in bioconjugation and click chemistry applications. Its thiol group (-SH) allows for specific attachment to cysteine residues or gold surfaces, while the azide group (-N3) facilitates efficient reactions with alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC). This makes it valuable for labeling proteins, peptides, and other biomolecules in research and drug development. Additionally, its PEG spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation processes. It is also employed in surface modification, nanomaterial functionalization, and the development of targeted drug delivery systems.