N-(Azido-PEG2)-N-Boc-PEG4-NHS ester
97%
Reagent
Code: #106329
CAS Number
2093153-95-6
blur_circular Chemical Specifications
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Molecular Information
Weight
619.66 g/mol
Formula
C₂₆H₄₅N₅O₁₂
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Storage & Handling
Storage
-20°C, dry, sealed
description Product Description
This compound is widely used in bioconjugation and chemical biology research. Its azide group enables click chemistry reactions, allowing for efficient and selective attachment to alkyne-functionalized molecules. The Boc-protected amine provides a versatile handle for further modifications after deprotection. The NHS ester moiety facilitates covalent coupling to primary amines, making it suitable for labeling proteins, peptides, and other biomolecules. The PEG spacers enhance solubility and reduce steric hindrance, improving reaction efficiency. Applications include the synthesis of antibody-drug conjugates, surface functionalization of nanoparticles, and development of targeted drug delivery systems. It is also employed in the preparation of bioconjugates for imaging, diagnostics, and therapeutic purposes.
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N-(Azido-PEG2)-N-Boc-PEG4-NHS ester
This compound is widely used in bioconjugation and chemical biology research. Its azide group enables click chemistry reactions, allowing for efficient and selective attachment to alkyne-functionalized molecules. The Boc-protected amine provides a versatile handle for further modifications after deprotection. The NHS ester moiety facilitates covalent coupling to primary amines, making it suitable for labeling proteins, peptides, and other biomolecules. The PEG spacers enhance solubility and reduce steric hindrance, improving reaction efficiency. Applications include the synthesis of antibody-drug conjugates, surface functionalization of nanoparticles, and development of targeted drug delivery systems. It is also employed in the preparation of bioconjugates for imaging, diagnostics, and therapeutic purposes.
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