(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3)
98%
Reagent
Code: #106734
CAS Number
1797406-80-4
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
645.77 g/mol
Formula
C₃₀H₄₃N₇O₇S
inventory_2
Storage & Handling
Storage
-20°C, airtight, dry
description Product Description
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3) is primarily used in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key linker molecule that connects an E3 ligase ligand to a target protein-binding moiety. Its triethylene glycol (PEG3) spacer ensures optimal distance and flexibility between the two components, enhancing the efficiency of the ternary complex formation. The azide (N3) group allows for further functionalization through click chemistry, enabling precise conjugation with various target-specific ligands. This makes it a valuable tool in drug discovery and chemical biology for studying protein function, identifying new therapeutic targets, and developing novel degradation-based therapies for diseases such as cancer and neurodegenerative disorders.
shopping_cart Available Sizes & Pricing
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3)
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3) is primarily used in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key linker molecule that connects an E3 ligase ligand to a target protein-binding moiety. Its triethylene glycol (PEG3) spacer ensures optimal distance and flexibility between the two components, enhancing the efficiency of the ternary complex formation. The azide (N3) group allows for further functionalization through click chemistry, enabling precise conjugation with various target-specific ligands. This makes it a valuable tool in drug discovery and chemical biology for studying protein function, identifying new therapeutic targets, and developing novel degradation-based therapies for diseases such as cancer and neurodegenerative disorders.
Mechanism | - |
Appearance | - |
Longevity | - |
Strength | - |
Storage | - |
Shelf Life | - |
Allergen(s) | - |
Dosage (Range) | - |
Recommended Dosage | - |
Dosage (Per Day) | - |
Recommended Dosage (Per Day) | - |
Mix Method | - |
Heat Resistance | - |
Stable in pH range | - |
Solubility | - |
Product Types | - |
INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
Total
฿0.00
THB