(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3)

98%

Reagent Code: #106734
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CAS Number 1797406-80-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 645.77 g/mol
Formula C₃₀H₄₃N₇O₇S
inventory_2 Storage & Handling
Storage -20°C, airtight, dry

description Product Description

(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3) is primarily used in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key linker molecule that connects an E3 ligase ligand to a target protein-binding moiety. Its triethylene glycol (PEG3) spacer ensures optimal distance and flexibility between the two components, enhancing the efficiency of the ternary complex formation. The azide (N3) group allows for further functionalization through click chemistry, enabling precise conjugation with various target-specific ligands. This makes it a valuable tool in drug discovery and chemical biology for studying protein function, identifying new therapeutic targets, and developing novel degradation-based therapies for diseases such as cancer and neurodegenerative disorders.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿54,990.00
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3)
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3) is primarily used in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key linker molecule that connects an E3 ligase ligand to a target protein-binding moiety. Its triethylene glycol (PEG3) spacer ensures optimal distance and flexibility between the two components, enhancing the efficiency of the ternary complex formation. The azide (N3) group allows for further functionalization through click chemistry, enabling precise conjugation with various target-specific ligands. This makes it a valuable tool in drug discovery and chemical biology for studying protein function, identifying new therapeutic targets, and developing novel degradation-based therapies for diseases such as cancer and neurodegenerative disorders.
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