Azido-PEG12-alcohol is widely used in bioconjugation and chemical biology due to its azide functional group, which enables efficient click chemistry reactions, particularly with alkynes. This compound is valuable in the synthesis of complex molecules, such as drug delivery systems, where it serves as a linker to attach bioactive molecules or targeting agents to polymers or nanoparticles. Its polyethylene glycol (PEG) spacer enhances solubility and reduces immunogenicity, making it suitable for applications in therapeutic development and diagnostics. Additionally, it is employed in the modification of surfaces, proteins, and peptides, facilitating the study of biomolecular interactions and the development of biosensors. Its versatility and biocompatibility make it a key reagent in pharmaceutical and biotechnological research.