Used extensively in bioconjugation and click chemistry, it serves as a versatile linker for attaching polyethylene glycol (PEG) chains to biomolecules, enhancing their solubility, stability, and biocompatibility. Commonly applied in drug delivery systems to improve the pharmacokinetics of therapeutic agents by prolonging circulation time and reducing immunogenicity. It is also utilized in the development of bioconjugates for targeted cancer therapies and diagnostic imaging agents. Additionally, it plays a role in surface modification of nanoparticles and materials for biomedical applications, enabling controlled release and targeted delivery.