This chemical is widely used as a crosslinking agent in bioconjugation and protein labeling applications. Its azido group allows for efficient click chemistry reactions, particularly with alkynes, enabling the attachment of biomolecules to surfaces or other molecules. The tetrafluorobenzene moiety enhances reactivity and stability, making it suitable for modifying peptides, proteins, and antibodies. It is also employed in the development of bioimaging probes and drug delivery systems, where precise and stable conjugation is critical. Additionally, its photoactivatable azide group is useful in photoaffinity labeling studies to investigate molecular interactions in biological systems.