2,6-difluoro-3-hydroxybenzamide
95%
Reagent
Code: #132991
CAS Number
951122-37-5
blur_circular Chemical Specifications
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Molecular Information
Weight
173.1169 g/mol
Formula
C₇H₅F₂NO₂
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Registry Numbers
MDL Number
MFCD18824499
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Storage & Handling
Storage
Room temperature, dry, sealed
description Product Description
Used in the synthesis of fluorinated pharmaceutical intermediates, particularly in the development of kinase inhibitors for cancer treatment. Its hydroxy and amide functional groups allow for hydrogen bonding, enhancing binding affinity to target proteins. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing effect of fluorine atoms, which improve metabolic stability and membrane permeability. Also utilized in agrochemical research for designing bioactive molecules with improved environmental stability.
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