1,3-Dihydro-1-(1,2,3,6-tetrahydro-4-pyridinyl)-2H-benzimidazole-2-one
97%
Reagent
Code: #170788
CAS Number
2147-83-3
blur_circular Chemical Specifications
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Molecular Information
Weight
215.26 g/mol
Formula
C₁₂H₁₃N₃O
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Registry Numbers
MDL Number
MFCD00044827
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Physical Properties
Melting Point
196°C
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used primarily in pharmaceutical research as a key intermediate in the synthesis of nicotinic acetylcholine receptor (nAChR) modulators. It serves as a structural analog in developing compounds targeting neurological disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia. Its scaffold supports binding affinity and selectivity for central nervous system receptors, making it valuable in optimizing drug candidates for cognitive enhancement and neuroprotection. Also employed in medicinal chemistry for structure-activity relationship (SAR) studies to improve metabolic stability and bioavailability of related therapeutics.
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