2,2-Difluoro-1,3-benzodioxole-5-carboxylic acid
97%
Reagent
Code: #170810
CAS Number
656-46-2
blur_circular Chemical Specifications
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Molecular Information
Weight
202.12 g/mol
Formula
C₈H₄F₂O₄
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Registry Numbers
MDL Number
MFCD00792417
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Physical Properties
Melting Point
178 °C
Boiling Point
266.1ºC at 760 mmHg
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Storage & Handling
Density
1.66
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals, particularly in the development of bioactive compounds where fluorine substitution enhances metabolic stability, lipophilicity, and binding affinity. Its structure allows for facile derivatization, making it valuable in medicinal chemistry for constructing novel heterocyclic systems. Commonly employed in the preparation of protease inhibitors and other therapeutic agents targeting viral and inflammatory diseases. Also utilized in the design of advanced materials due to the electron-withdrawing properties and stability imparted by the difluoromethylene-dioxole moiety.
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