tert-Butyl (3-cyano-7-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophen-2-yl)carbamate

≥95%

Reagent Code: #141676
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CAS Number 2761968-90-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 418.29 g/mol
Formula C₂₀H₂₄BFN₂O₄S
thermostat Physical Properties
Boiling Point 514.4±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.25±0.1 g/cm3(Predicted)
Storage 2-8°C

description Product Description

Used as an intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical development. The presence of the cyano and fluoro groups enhances reactivity and selectivity in coupling processes. The boronate ester allows for efficient carbon-carbon bond formation, making it valuable in constructing complex aromatic systems found in drug candidates. Commonly applied in the preparation of kinase inhibitors and other therapeutic agents requiring substituted benzo[b]thiophene scaffolds. Its tert-butyl carbamate (Boc) protecting group ensures amine functionality remains intact during reactions, enabling sequential synthetic strategies in medicinal chemistry.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,280.00
inventory 250mg
10-20 days ฿7,280.00
inventory 1g
10-20 days ฿18,820.00

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