1-Hydroxy-6-(trifluoromethyl)benzo[c][1,2]oxaborol-3(1H)-one

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Reagent Code: #192856
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CAS Number 2828438-87-3

science Other reagents with same CAS 2828438-87-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 215.92 g/mol
Formula C₈H₄BF₃O₃
thermostat Physical Properties
Boiling Point 289.7±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.51±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in the synthesis of boron-containing pharmaceuticals, particularly in the development of proteasome inhibitors for cancer therapy. Its unique boron heterocycle structure enhances binding affinity to target enzymes, improving drug efficacy. Also employed in agrochemicals for creating novel fungicides due to its metabolic stability and bioavailability. The trifluoromethyl group contributes to increased lipophilicity and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active compounds.

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿5,060.00
250mg
10-20 days ฿8,580.00
1-Hydroxy-6-(trifluoromethyl)benzo[c][1,2]oxaborol-3(1H)-one
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Used as a key intermediate in the synthesis of boron-containing pharmaceuticals, particularly in the development of proteasome inhibitors for cancer therapy. Its unique boron heterocycle structure enhances binding affinity to target enzymes, improving drug efficacy. Also employed in agrochemicals for creating novel fungicides due to its metabolic stability and bioavailability. The trifluoromethyl group contributes to increased lipophilicity and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active compounds.
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