4-Fluoro-2-(trifluoromethyl)benzyl bromide
98%
Reagent
Code: #118898
Alias
4-Fluoro-2-(trifluoromethyl)benzyl bromide
CAS Number
206860-48-2
blur_circular Chemical Specifications
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Molecular Information
Weight
257.02 g/mol
Formula
C₈H₅BrF₄
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Registry Numbers
EC Number
000-000-0
MDL Number
MFCD00061176
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Physical Properties
Boiling Point
141 °C(lit.)
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Storage & Handling
Density
1.665 g/mL at 25 °C(lit.)
Storage
room temperature
description Product Description
This compound is primarily utilized in organic synthesis as a versatile building block for the preparation of more complex molecules. Its benzyl bromide group makes it a valuable reagent for introducing the 4-fluoro-2-(trifluoromethyl)benzyl moiety into various substrates through nucleophilic substitution reactions. It is particularly useful in the development of pharmaceuticals and agrochemicals, where the incorporation of fluorine atoms can enhance the biological activity, metabolic stability, and lipophilicity of the target compounds. Additionally, it serves as an intermediate in the synthesis of specialty chemicals, including dyes, polymers, and materials with unique electronic or optical properties. Its trifluoromethyl group is especially significant in medicinal chemistry, as it often improves binding affinity and selectivity in drug candidates.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Purity (HPLC) | 98-100% |
Purity (Neutralization Titration) | 97.5-102.5 |
Refractive Index (N20/D) | 1.481-1.483 |
Specific Gravity (20/20) | 1.664-1.666 |
Appearance | Colorless to Yellow Liquid |
Infrared Spectrometry | Conforms To Structure |
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4-Fluoro-2-(trifluoromethyl)benzyl bromide
This compound is primarily utilized in organic synthesis as a versatile building block for the preparation of more complex molecules. Its benzyl bromide group makes it a valuable reagent for introducing the 4-fluoro-2-(trifluoromethyl)benzyl moiety into various substrates through nucleophilic substitution reactions. It is particularly useful in the development of pharmaceuticals and agrochemicals, where the incorporation of fluorine atoms can enhance the biological activity, metabolic stability, and lipophilicity of the target compounds. Additionally, it serves as an intermediate in the synthesis of specialty chemicals, including dyes, polymers, and materials with unique electronic or optical properties. Its trifluoromethyl group is especially significant in medicinal chemistry, as it often improves binding affinity and selectivity in drug candidates.
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