4-Fluoro-2-(trifluoromethyl)benzyl bromide

98%

Reagent Code: #118898
label
Alias 4-Fluoro-2-(trifluoromethyl)benzyl bromide
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CAS Number 206860-48-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 257.02 g/mol
Formula C₈H₅BrF₄
badge Registry Numbers
EC Number 000-000-0
MDL Number MFCD00061176
thermostat Physical Properties
Boiling Point 141 °C(lit.)
inventory_2 Storage & Handling
Density 1.665 g/mL at 25 °C(lit.)
Storage room temperature

description Product Description

This compound is primarily utilized in organic synthesis as a versatile building block for the preparation of more complex molecules. Its benzyl bromide group makes it a valuable reagent for introducing the 4-fluoro-2-(trifluoromethyl)benzyl moiety into various substrates through nucleophilic substitution reactions. It is particularly useful in the development of pharmaceuticals and agrochemicals, where the incorporation of fluorine atoms can enhance the biological activity, metabolic stability, and lipophilicity of the target compounds. Additionally, it serves as an intermediate in the synthesis of specialty chemicals, including dyes, polymers, and materials with unique electronic or optical properties. Its trifluoromethyl group is especially significant in medicinal chemistry, as it often improves binding affinity and selectivity in drug candidates.

format_list_bulleted Product Specification

Test Parameter Specification
Purity (HPLC) 98-100%
Purity (Neutralization Titration) 97.5-102.5
Refractive Index (N20/D) 1.481-1.483
Specific Gravity (20/20) 1.664-1.666
Appearance Colorless to Yellow Liquid
Infrared Spectrometry Conforms To Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25g
10-20 days ฿22,400.00
inventory 250mg
10-20 days ฿520.00
inventory 1g
10-20 days ฿1,220.00
inventory 5g
10-20 days ฿4,780.00
4-Fluoro-2-(trifluoromethyl)benzyl bromide
This compound is primarily utilized in organic synthesis as a versatile building block for the preparation of more complex molecules. Its benzyl bromide group makes it a valuable reagent for introducing the 4-fluoro-2-(trifluoromethyl)benzyl moiety into various substrates through nucleophilic substitution reactions. It is particularly useful in the development of pharmaceuticals and agrochemicals, where the incorporation of fluorine atoms can enhance the biological activity, metabolic stability, and lipophilicity of the target compounds. Additionally, it serves as an intermediate in the synthesis of specialty chemicals, including dyes, polymers, and materials with unique electronic or optical properties. Its trifluoromethyl group is especially significant in medicinal chemistry, as it often improves binding affinity and selectivity in drug candidates.
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