Bufuralol hydrochloride is primarily used in pharmacological research as a beta-adrenergic receptor antagonist. It is often employed in studies to understand the mechanisms of beta-blockers and their effects on the cardiovascular system. Researchers utilize it to investigate the binding affinity and selectivity of beta-adrenoceptors, which helps in developing drugs for conditions like hypertension, arrhythmias, and angina. Additionally, it serves as a tool compound in experimental models to explore the physiological and biochemical responses mediated by beta-adrenergic receptors. Its application extends to studying the impact of beta-blockade on heart rate, blood pressure, and other autonomic functions in both in vitro and in vivo settings.