1-[2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-fluorophenyl]-1-butanone
95%
Reagent
Code: #167938
CAS Number
64552-17-6
blur_circular Chemical Specifications
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Molecular Information
Weight
311.3916 g/mol
Formula
C₁₇H₂₆FNO₃
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Registry Numbers
MDL Number
MFCD00864575
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Physical Properties
Melting Point
88-89 °C
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as an intermediate in the synthesis of beta-adrenergic receptor antagonists, particularly in the production of certain cardioselective beta-blockers. Its structure supports the development of compounds with high selectivity for β1-adrenergic receptors, making it valuable in treating hypertension, angina, and arrhythmias. The fluorinated aromatic core combined with the hydroxypropoxy and tertiary amino groups enhances binding affinity and metabolic stability in final drug products. It is employed in pharmaceutical research and development for optimizing drug efficacy and pharmacokinetic profiles.
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