Ceftiofur sodium is widely used in veterinary medicine as a broad-spectrum antibiotic for the treatment of bacterial infections in livestock and companion animals. It is particularly effective against respiratory diseases in cattle, such as bovine respiratory disease (BRD), caused by pathogens like Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. The compound is also used to treat infections in swine, including swine dysentery and respiratory tract infections. Due to its rapid absorption and conversion to active metabolites, ceftiofur sodium provides fast-acting and prolonged antibacterial activity. It is commonly administered via intramuscular or subcutaneous injection. Its use supports improved animal health and reduced disease spread in herds, contributing to more efficient livestock production. However, its application is carefully regulated to minimize the risk of antibiotic resistance development.