Piperacillin is widely used in the medical field as an antibiotic to treat a variety of bacterial infections. It is particularly effective against infections caused by Pseudomonas aeruginosa, a common pathogen in hospital settings. The drug is often administered intravenously to treat severe infections such as pneumonia, urinary tract infections, septicemia, and intra-abdominal infections. Piperacillin is frequently combined with tazobactam, a beta-lactamase inhibitor, to enhance its efficacy against beta-lactamase-producing bacteria, which are otherwise resistant to many antibiotics. This combination is especially useful in treating complicated and multi-drug-resistant infections. Piperacillin is also employed in surgical prophylaxis to prevent infections during and after procedures. Its broad-spectrum activity makes it a critical tool in managing infections in immunocompromised patients, such as those undergoing chemotherapy or organ transplants. However, its use requires careful monitoring due to potential side effects, including allergic reactions and antibiotic resistance.