Ceftibuten hydrate is a third-generation cephalosporin antibiotic primarily used to treat various bacterial infections. It is effective against respiratory tract infections, including upper respiratory infections like sinusitis, and lower respiratory infections such as bronchitis and pneumonia, as well as ear infections like otitis media. Additionally, it is prescribed for urinary tract infections, such as cystitis and pyelonephritis, caused by susceptible bacteria, particularly gram-negative and some gram-positive strains. The medication works by inhibiting bacterial cell wall synthesis, thereby stopping the growth and spread of the infection, reducing inflammation. It is often chosen for its oral bioavailability, making it convenient for outpatient treatment. Ceftibuten hydrate is particularly useful for patients who may have allergies to other classes of antibiotics, such as penicillins. Proper use and adherence to prescribed dosages are crucial to ensure effectiveness and reduce the risk of antibiotic resistance.