OM99-2 is primarily used in biochemical research as a potent inhibitor of β-secretase (BACE-1), an enzyme involved in the production of amyloid-beta peptides. These peptides are associated with the formation of amyloid plaques in the brain, which are a hallmark of Alzheimer's disease. Researchers utilize OM99-2 to study the mechanisms of BACE-1 and to develop potential therapeutic strategies for Alzheimer's. Its application is crucial in understanding enzyme inhibition and in the screening of new drugs aimed at reducing amyloid-beta production.