This compound is widely used in bioconjugation and click chemistry applications due to its bifunctional nature. The azide group reacts efficiently with alkyne-containing molecules in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling the formation of stable triazole linkages. This property makes it valuable for labeling biomolecules, such as proteins, peptides, and nucleic acids, without disrupting their biological activity. Additionally, the PEG8 spacer provides solubility, flexibility, and reduced steric hindrance, enhancing its utility in creating biocompatible conjugates. It is particularly useful in drug delivery systems, where it facilitates the attachment of targeting ligands to therapeutic agents, improving specificity and efficacy. Furthermore, it is employed in material science for surface modification and functionalization of polymers or nanoparticles, enabling the development of advanced biomaterials.