20-carboxy Leukotriene B4 is primarily studied in the context of inflammation and immune response regulation. It is a metabolite of Leukotriene B4, a potent mediator of inflammation, and plays a role in modulating inflammatory processes. Research focuses on its potential as a biomarker for inflammatory diseases, such as asthma, rheumatoid arthritis, and psoriasis, where its levels can indicate the severity or progression of the condition. Additionally, it is investigated for its role in resolving inflammation, as it may help in understanding the mechanisms of inflammatory resolution and developing targeted therapies for chronic inflammatory disorders.