BT-11
10mM in DMSO
Reagent
Code: #142758
CAS Number
1912399-75-7
science Other reagents with same CAS 1912399-75-7
blur_circular Chemical Specifications
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Molecular Information
Weight
528.5599999999999 g/mol
Formula
C₃₀H₂₄N₈O₂
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Storage & Handling
Storage
-20°C
description Product Description
BT-11 is primarily used in research settings for its selective activation of the nuclear receptor RORγt, which plays a key role in the differentiation of T helper 17 (Th17) cells. Due to this action, BT-11 has shown promise in preclinical studies for modulating immune responses, particularly in models of inflammatory and autoimmune diseases such as multiple sclerosis, psoriasis, and inflammatory bowel disease (IBD). Its ability to locally suppress pathological inflammation in the gut without causing systemic immunosuppression makes it a candidate for targeted therapies in gastrointestinal disorders. BT-11 is not used clinically and remains an investigational tool compound in immunology and drug development.
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