Used as a highly reactive acylating agent in organic synthesis, particularly for introducing trifluoroacetyl groups into amines and alcohols. It is especially valuable in peptide chemistry and bioconjugation for temporary protection of amino groups due to the ease of removing the trifluoroacetyl moiety under mild conditions. Its N-hydroxysuccinimide ester functionality enhances selectivity and efficiency in coupling reactions, making it useful in the preparation of active esters for protein labeling and drug design. Commonly employed in the synthesis of pharmaceuticals and agrochemicals where fluorinated groups improve metabolic stability and lipophilicity.