Used in bioconjugation chemistry, particularly in the preparation of antibody-drug conjugates (ADCs). It serves as a key intermediate in the synthesis of cleavable disulfide linkers, enabling controlled release of therapeutic agents in targeted drug delivery systems. Its thiol-reactive pyridyl disulfide group facilitates efficient and selective coupling with thiol-containing biomolecules under mild conditions. Commonly employed in the development of biopharmaceuticals and diagnostic probes where precise linkage between proteins and payloads is required. Also utilized in surface modification of nanoparticles and biosensors due to its ability to form stable disulfide bonds.