Used in bioconjugation and labeling of biomolecules due to its isothiocyanate group, which readily reacts with primary amines in proteins and peptides to form stable thiourea derivatives. Commonly employed in fluorescent probe development, especially when combined with fluorophores, enabling detection and imaging in biological systems. The picolyl moiety enhances metal-binding properties, making it useful in designing sensors for transition metal ions in environmental or physiological samples. Also applied in solid-phase synthesis and affinity tagging for studying molecular interactions in biochemical assays.